Palpitations during antihypertensive treatment with calcium antagonists

Dihydropyridine Calcium- Channel Blockers for Antihypertensive Treatment

Subjects. Patients aged :<:: 60 years with sitting systolic blood pressure (BP) 160 219 mmHg and sitting diastolic BP< 95 mmHg during run-in phase. Methods and Results. Four thousand, six hundred and ninety-five patients were randomly assigned to active treatment (N = 2 398), i.e. nitrendipine, with the possible addition of enalapril and hydrochlorothiazide, or to matching placebos (N = 2 297)....

Eosinophilia during psoriasis treatment with TNF antagonists.

Serum lipoproteins during treatment with the antihypertensive agent indapamide.

Considering the documented, potentially undesirable influence of various thiazide-type or loop diuretics on serum lipoproteins, we prospectively investigated in 69 men (mean age +/- SEM, 32 +/- 1 years) the metabolic effects of the new diuretic-antihypertensive compound indapamide. Compared to placebo, indapamide (2.5 mg/day) given for 6 to 8 weeks lowered (p less than 0.02 to less than 0.001) ...

Atherosclerosis, calcium, and calcium antagonists.

Review of salt restriction and the response to antihypertensive drugs. Satellite symposium on calcium antagonists.

We evaluated the response to salt restriction in hypertensive patients receiving drugs. By restricting their salt intake to less than 80 mmol of sodium per day for 3 months, 50% of patients reaching goal compliance were able to discontinue diuretics. The literature also reveals responses to a low salt diet. Salt restriction augmented the hypotensive effect of chlorthalidone in two investigation...